Trends in Preeclampsia Risk Factors in the US From 2010 to 2021 (2024)

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    Research Letter

    June10, 2024

    Mariam K.Ayyash,MD, MSCR1; RodneyMcLarenJr,MD2; MajidShaman,MD3; et al Huda B.Al-Kouatly,MD2

    Author Affiliations Article Information

    • 1Division of Maternal-Fetal Medicine, Columbia University Irving Medical Center, New York, New York

    • 2Division of Maternal-Fetal Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania

    • 3Division of Maternal-Fetal Medicine, Henry Ford Health, Detroit, Michigan

    JAMA. Published online June 10, 2024. doi:10.1001/jama.2024.8931

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    Preeclampsia is associated with substantial maternal and neonatal morbidity and mortality.1 High risk factors for preeclampsia include chronic hypertension, pregestational diabetes, history of preeclampsia, multifetal gestation, autoimmune disease, and kidney disease. Moderate risk factors include nulliparity, advanced maternal age (defined as ≥35 years), body mass index (calculated as weight in kilograms divided by height in meters squared) greater than 30, interpregnancy interval of greater than or equal to 10 years, family history of preeclampsia, certain sociodemographic characteristics (Black race, low socioeconomic status), and in vitro fertilization (IVF).1 Trends in risk factors have not been evaluated since a study in a single medical center using data from 1988 to 2014.2 Thus, this study evaluated trends in preeclampsia risk factors in the US between 2010 and 2021.

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    Ayyash MK, McLaren R, Shaman M, Al-Kouatly HB. Trends in Preeclampsia Risk Factors in the US From 2010 to 2021. JAMA. Published online June 10, 2024. doi:10.1001/jama.2024.8931

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